6IW8

Crystal structure of Importin-alpha and wild-type GM130

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Peptide from Golgin subfamily A member 2	polymer	53	5769.6	1	UniProt (Q08379)	Homo sapiens (Human)	130 kDa cis-Golgi matrix protein,GM130,GM130 autoantigen,Golgin-95
2	B (C)	Importin subunit alpha-1	polymer	433	46898.7	1	UniProt (P52293) Pfam (PF01749) Pfam (PF00514) Pfam (PF16186)	Mus musculus (Mouse)	Importin alpha P1,Karyopherin subunit alpha-2,Pendulin,Pore targeting complex 58 kDa subunit,PTAC58,RAG cohort protein 1,SRP1-alpha
3	C, D (A, C)	water	water		18.0	12	Chemie (HOH)

Sequence modifications

A: 1 - 48 (UniProt: Q08379)

PDB	External Database	Details
Gly -4	-	expression tag
Pro -3	-	expression tag
Leu -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

C: 70 - 498 (UniProt: P52293)

PDB	External Database	Details
Gly 66	-	expression tag
Ser 67	-	expression tag
His 68	-	expression tag
Met 69	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	52668.3
All*	Total formula weight	52668.3

*Water molecules are not included.