6IUH

Crystal structure of GIT1 PBD domain in complex with Liprin-alpha2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	ARF GTPase-activating protein GIT1	polymer	132	14692.9	2	UniProt (Q9Z272) Pfam (PF12205)	Rattus norvegicus (Rat)	ARF GAP GIT1,Cool-associated and tyrosine-phosphorylated protein 1,CAT1,G protein-coupled receptor kinase-interactor 1,GRK-interacting protein 1
2	C, D (C, D)	Liprin-alpha-2	polymer	36	4032.5	2	UniProt (O75334)	Homo sapiens (Human)	Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2,PTPRF-interacting protein alpha-2
3	E, F, G (A, B)	IODIDE ION	non-polymer		126.9	3	Chemie (IOD)
4	H, I, J, K (A, B, C, D)	water	water		18.0	141	Chemie (HOH)

Sequence modifications

A, B: 645 - 770 (UniProt: Q9Z272)

PDB	External Database	Details
Gly 639	-	expression tag
Pro 640	-	expression tag
Gly 641	-	expression tag
Ser 642	-	expression tag
Glu 643	-	expression tag
Phe 644	-	expression tag

C, D: 642 - 671 (UniProt: O75334)

PDB	External Database	Details
Gly 636	-	expression tag
Pro 637	-	expression tag
Gly 638	-	expression tag
Ser 639	-	expression tag
Glu 640	-	expression tag
Phe 641	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	37450.7
Non-Polymers*	Number of molecules	3
	Total formula weight	380.7
All*	Total formula weight	37831.4

*Water molecules are not included.