6IRF
Structure of the human GluN1/GluN2A NMDA receptor in the glutamate/glycine-bound state at pH 6.3, Class I
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Glutamate receptor ionotropic, NMDA 1 | polymer | 847 | 95336.2 | 2 | UniProt (Q05586) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) In PDB | Homo sapiens (Human) | N-methyl-D-aspartate receptor subunit NR1,NMD-R1 |
2 | B, D | Glutamate receptor ionotropic, NMDA 2A | polymer | 841 | 94192.2 | 2 | UniProt (Q12879) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) In PDB | Homo sapiens (Human) | N-methyl D-aspartate receptor subtype 2A,hNR2A |
Sequence modifications
A, C: 1 - 847 (UniProt: Q05586)
B, D: 1 - 841 (UniProt: Q12879)
PDB | External Database | Details |
---|---|---|
Arg 612 | Gly 612 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Arg 656 | Glu 656 | engineered mutation |
Arg 657 | Glu 657 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 379056.8 | |
All* | Total formula weight | 379056.8 |