6IRD

Complex structure of INADL PDZ89 and PLCb4 C-terminal CC-PBM

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (B)	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase	polymer	266	31063.7	1	UniProt (Q91UZ1) Pfam (PF08703)	Mus musculus (Mouse)
2	B (C)	InaD-like protein	polymer	216	22723.5	1	UniProt (Q8NI35) Pfam (PF00595)	Homo sapiens (Human)	hINADL,Pals1-associated tight junction protein,Protein associated to tight junctions
3	C, D, E, F, G (B, C)	GOLD ION	non-polymer		197.0	5	Chemie (AU)

Sequence modifications

B: 1 - 264 (UniProt: Q91UZ1)

PDB	External Database	Details
Glu -1	-	expression tag
Gly 0	-	expression tag
Ala 15	Lys 926	engineered mutation
Ala 19	Lys 930	engineered mutation
Ala 22	Lys 933	engineered mutation
Ala 23	Lys 934	engineered mutation
Ala 26	Lys 937	engineered mutation
Ala 33	Lys 944	engineered mutation
Ala 34	Lys 945	engineered mutation
Ala 37	Lys 948	engineered mutation

C: 266 - 469 (UniProt: Q8NI35)

PDB	External Database	Details
Gly 470	-	expression tag
Gly 471	-	expression tag
Gly 472	-	expression tag
Ser 473	-	expression tag
Gly 474	-	expression tag
Gly 475	-	expression tag
Gly 476	-	expression tag
Gly 477	-	expression tag
Ser 478	-	expression tag
Gly 479	-	expression tag
Gly 480	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	53787.2
Non-Polymers*	Number of molecules	5
	Total formula weight	984.8
All*	Total formula weight	54772.1

*Water molecules are not included.