6IR9
RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-1) of the nucleosome
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA-directed RNA polymerase subunit | polymer | 1743 | 194107.4 | 1 | UniProt (C4R4Y0) Pfam (PF04997) Pfam (PF05001) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) Pfam (PF04992) Pfam (PF04990) | Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) | |
| 2 | B (B) | DNA-directed RNA polymerase subunit beta | polymer | 1227 | 139746.1 | 1 | UniProt (C4QZQ7) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF04566) Pfam (PF04567) Pfam (PF00562) Pfam (PF04560) | Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) | |
| 3 | C (C) | RNA polymerase II third largest subunit B44, part of central core | polymer | 304 | 34216.3 | 1 | UniProt (C4R7L2) Pfam (PF01193) Pfam (PF01000) | Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) | |
| 4 | D (D) | RNA polymerase II subunit B32 | polymer | 186 | 20623.0 | 1 | UniProt (C4R2U9) Pfam (PF03874) | Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) | |
| 5 | E (E) | RNA polymerase subunit ABC27, common to RNA polymerases I, II, and III | polymer | 214 | 24962.7 | 1 | UniProt (C4R3P8) Pfam (PF03871) Pfam (PF01191) | Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) | |
| 6 | F (F) | RNA polymerase subunit ABC23, common to RNA polymerases I, II, and III | polymer | 155 | 17803.6 | 1 | UniProt (C4R1V1) Pfam (PF01192) | Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) | |
| 7 | G (G) | RNA polymerase II subunit | polymer | 171 | 18802.6 | 1 | UniProt (C4R9A1) Pfam (PF03876) Pfam (PF00575) | Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) | |
| 8 | H (H) | DNA-directed RNA polymerases I, II, and III subunit RPABC3 | polymer | 145 | 16249.2 | 1 | UniProt (C4R273) Pfam (PF03870) | Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) | |
| 9 | I (I) | DNA-directed RNA polymerase subunit | polymer | 115 | 13612.3 | 1 | UniProt (F2QPE6) Pfam (PF02150) Pfam (PF01096) | Komagataella phaffii (strain ATCC 76273 / CBS 7435 / CECT 11047 / NRRL Y-11430 / Wegner 21-1) (Yeast) | |
| 10 | J (J) | RNA polymerase subunit ABC10-beta, common to RNA polymerases I, II, and III | polymer | 72 | 8554.1 | 1 | UniProt (C4R009) Pfam (PF01194) | Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) | |
| 11 | K (K) | RNA polymerase II subunit B12.5 | polymer | 118 | 13832.9 | 1 | UniProt (C4R3Z5) Pfam (PF13656) | Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) | |
| 12 | L (L) | RNA polymerase subunit ABC10-alpha | polymer | 72 | 7862.0 | 1 | UniProt (F2QMI1) Pfam (PF03604) | Komagataella phaffii (strain ATCC 76273 / CBS 7435 / CECT 11047 / NRRL Y-11430 / Wegner 21-1) (Yeast) | |
| 13 | M (P) | RNA (5'-R(P*GP*CP*CP*UP*GP*GP*UP*GP*UP*CP*UP*UP*GP*GP*GP*U)-3') | polymer | 16 | 5124.0 | 1 | synthetic construct | ||
| 14 | N (T) | DNA (198-MER) | polymer | 198 | 60870.0 | 1 | synthetic construct | ||
| 15 | O (N) | DNA (198-MER) | polymer | 198 | 61381.9 | 1 | synthetic construct | ||
| 16 | P (M) | Transcription elongation factor 1 homolog | polymer | 113 | 12606.9 | 1 | UniProt (C4QZ45) Pfam (PF05129) | Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) | |
| 17 | Q (V) | Transcription elongation factor SPT4 | polymer | 108 | 12039.6 | 1 | UniProt (C4R0E6) Pfam (PF06093) | Komagataella phaffii (Yeast) | |
| 18 | R (W) | Spt5 | polymer | 911 | 101459.4 | 1 | UniProt (C4R370) Pfam (PF11942) Pfam (PF03439) Pfam (PF00467) Pfam (PF12815) | Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) | Protein that forms a complex with Spt4p |
| 19 | S, W (a, e) | Histone H3.3 | polymer | 139 | 15643.3 | 2 | UniProt (P84243) Pfam (PF00125) | Homo sapiens (Human) | |
| 20 | T, X (b, f) | Histone H4 | polymer | 106 | 11676.7 | 2 | UniProt (P62805) Pfam (PF15511) | Homo sapiens (Human) | |
| 21 | U, Y (c, g) | Histone H2A type 1-B/E | polymer | 133 | 14447.8 | 2 | UniProt (P04908) Pfam (PF00125) Pfam (PF16211) | Homo sapiens (Human) | Histone H2A.2,Histone H2A/a,Histone H2A/m |
| 22 | V, Z (d, h) | Histone H2B type 1-J | polymer | 129 | 14217.5 | 2 | UniProt (P06899) Pfam (PF00125) | Homo sapiens (Human) | Histone H2B.1,Histone H2B.r,H2B/r |
| 23 | AA, BA, DA, EA, FA... (A, B, C, I, J...) | ZINC ION | non-polymer | 65.4 | 10 | Chemie (ZN) | |||
| 24 | CA (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) |
Sequence modifications
M: 1 - 110 (UniProt: C4QZ45)
V: 8 - 114 (UniProt: C4R0E6)
W: 1 - 908 (UniProt: C4R370)
a, e: 0 - 135 (UniProt: P84243)
b, f: 0 - 102 (UniProt: P62805)
c, g: 0 - 129 (UniProt: P04908)
d, h: -3 - 122 (UniProt: P06899)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| Gly 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 7 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| Gly 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -6 | - | expression tag |
| Ser -5 | - | expression tag |
| His -4 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 26 |
| Total formula weight | 875824.7 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 678.4 | |
| All* | Total formula weight | 876503.1 |
