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6IPD

Post-catalytic Complex of Human DNA Polymerase Mu with Templating Adenine and Mn-8oxodGMP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ADNA-directed DNA/RNA polymerase mupolymer35640054.41UniProt (Q9NP87)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
In PDB
Homo sapiens (Human)Pol Mu,Terminal transferase
2TDNA (5'-D(*CP*GP*GP*CP*AP*TP*AP*CP*G)-3')polymer92740.81synthetic construct
3PDNA (5'-D(*CP*GP*TP*AP*(8OG))-3')polymer51536.01synthetic construct
4DDNA (5'-D(P*GP*CP*CP*G)-3')polymer41191.81synthetic construct
5AMANGANESE (II) IONnon-polymer54.92Chemie (MN)
6ASODIUM IONnon-polymer23.02Chemie (NA)
7AOXALIC ACIDnon-polymer90.01Chemie (OXD)
8A4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACIDnon-polymer238.31Chemie (EPE)
9A1,2-ETHANEDIOLnon-polymer62.13Chemie (EDO)
10waterwater18.0419Chemie (HOH)
Sequence modifications
A: 132 - 397 (UniProt: Q9NP87)
PDBExternal DatabaseDetails
Gly 127-expression tag
Ser 128-expression tag
Ala 129-expression tag
Ala 130-expression tag
Ala 131-expression tag
A: 411 - 494 (UniProt: Q9NP87)
PDBExternal DatabaseDetails
Gly 410-linker
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight45523.1
Non-Polymers*Number of molecules9
Total formula weight670.4
All*Total formula weight46193.5
*Water molecules are not included.

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PDB entries from 2024-03-27

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