6INL
Crystal structure of CDK2 IN complex with Inhibitor CVT-313
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Cyclin-dependent kinase 2 | polymer | 299 | 34063.6 | 1 | UniProt (P24941) Pfam (PF00069) In PDB | Homo sapiens (Human) | Cell division protein kinase 2,p33 protein kinase |
| 2 | A | 2,2'-{[6-{[(4-methoxyphenyl)methyl]amino}-9-(propan-2-yl)-9H-purin-2-yl]azanediyl}di(ethan-1-ol) | non-polymer | 400.5 | 1 | Chemie (AJR) | |||
| 3 | water | water | 18.0 | 153 | Chemie (HOH) |
Sequence modifications
A: 1 - 298 (UniProt: P24941)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34063.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 400.5 | |
| All* | Total formula weight | 34464.0 |
