6ILQ
Crystal structure of PPARgamma with compound BR101549
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Peroxisome proliferator-activated receptor gamma | polymer | 272 | 31094.1 | 1 | UniProt (P37231) Pfam (PF00104) In PDB | Homo sapiens (Human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
2 | B | Nuclear receptor coactivator 1 | polymer | 25 | 2806.2 | 1 | UniProt (Q15788) Pfam (PF08832) In PDB | Homo sapiens | NCoA-1,Class E basic helix-loop-helix protein 74,bHLHe74,Protein Hin-2,RIP160,Renal carcinoma antigen NY-REN-52,Steroid receptor coactivator 1,SRC-1 |
3 | A | ethyl [2-butyl-6-oxo-1-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl]methyl}-4-(propan-2-yl)-1,6-dihydropyrimidin-5-yl]acetate | non-polymer | 530.6 | 1 | Chemie (AE0) | |||
4 | water | water | 18.0 | 63 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 33900.3 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 530.6 | |
All* | Total formula weight | 34430.9 |