6IHI
Crystal structure of RasADH 3B3/I91V from Ralstonia.sp in complex with NADPH and A6O
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Alclohol dehydrogenase | polymer | 249 | 26645.2 | 4 | UniProt (C0IR58) | Ralstonia sp. | |
| 2 | E, G, H (A, B, C) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 3 | Chemie (NAP) | |||
| 3 | F, I (A, C) | (2R,3S)-2-ethyl-2-[(2E)-2-(6-methoxy-3,4-dihydro-2H-naphthalen-1-ylidene)ethyl]-3-oxidanyl-cyclopentan-1-one | non-polymer | 314.4 | 2 | Chemie (A6O) | |||
| 4 | J, K, L, M (A, B, C, D) | water | water | 18.0 | 730 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 249 (UniProt: C0IR58)
| PDB | External Database | Details |
|---|---|---|
| Val 91 | Ile 91 | engineered mutation |
| Ser 187 | Ile 187 | engineered mutation |
| Leu 188 | Ile 188 | engineered mutation |
| Ala 205 | Phe 205 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 106580.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 2859.1 | |
| All* | Total formula weight | 109439.7 |
