6IH7
Crystal structure of a standalone versatile EAL protein from Vibrio cholerae O395 - 3',3'-cGAMP bound form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | cyclic di nucleotide phoshodiesterase | polymer | 257 | 29025.1 | 2 | UniProt (A0A0H3AJ04) Pfam (PF00563) | Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395) | |
| 2 | C, F (B, A) | 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one | non-polymer | 674.4 | 2 | Chemie (4BW) | |||
| 3 | D, E, G, H (B, A) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 4 | I, J (B, A) | water | water | 18.0 | 61 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 257 (UniProt: A0A0H3AJ04)
| PDB | External Database | Details |
|---|---|---|
| Ser 15 | Cys 15 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58050.2 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1509.1 | |
| All* | Total formula weight | 59559.3 |
