6IH6
Phosphite Dehydrogenase mutant I151R/P176R/M207A from Ralstonia sp. 4506 in complex with non-natural cofactor Nicotinamide Cytosine dinucleotide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Phosphite dehydrogenase | polymer | 338 | 36913.7 | 4 | UniProt (G4XDR8) Pfam (PF00389) Pfam (PF02826) | Ralstonia sp. 4506 | |
| 2 | E, F (A, B) | [[(2S,3S,4R,5S)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4R,5S)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | non-polymer | 640.4 | 2 | Chemie (A7R) | |||
| 3 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 213 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 336 (UniProt: G4XDR8)
| PDB | External Database | Details |
|---|---|---|
| Arg 151 | Ile 151 | engineered mutation |
| Arg 176 | Pro 176 | engineered mutation |
| Ala 207 | Met 207 | engineered mutation |
| Leu 337 | - | expression tag |
| Glu 338 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 147654.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1280.8 | |
| All* | Total formula weight | 148935.6 |
