6IH5
Crystal structure of Phosphite Dehydrogenase mutant I151R/P176E from Ralstonia sp. 4506 in complex with non-natural cofactor Nicotinamide Cytosine dinucleotide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Phosphite dehydrogenase | polymer | 338 | 36945.7 | 2 | UniProt (G4XDR8) Pfam (PF00389) Pfam (PF02826) | Ralstonia sp. 4506 | |
| 2 | C (B) | [[(2S,3S,4R,5S)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4R,5S)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | non-polymer | 640.4 | 1 | Chemie (A7R) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 118 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 336 (UniProt: G4XDR8)
| PDB | External Database | Details |
|---|---|---|
| Arg 151 | Ile 151 | engineered mutation |
| Glu 176 | Pro 176 | engineered mutation |
| Leu 337 | - | expression tag |
| Glu 338 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 73891.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 640.4 | |
| All* | Total formula weight | 74531.9 |
