6IEO

Crystal structure of Mycobacterium tuberculosis HtrA1 (Rv1223) in regulated conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Probable serine protease HtrA (DEGP protein)	polymer	314	32522.4	1	UniProt (O06291) Pfam (PF13365) Pfam (PF13180) In PDB	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	DegQ like protein
2	A	phenylmethanesulfonic acid	non-polymer		172.2	1	Chemie (PMS)
3		water	water		18.0	138	Chemie (HOH)

Sequence modifications

A: 224 - 528 (UniProt: O06291)

PDB	External Database	Details
Met 223	-	initiating methionine
Leu 529	-	expression tag
Glu 530	-	expression tag
His 531	-	expression tag
His 532	-	expression tag
His 533	-	expression tag
His 534	-	expression tag
His 535	-	expression tag
His 536	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	32522.4
Non-Polymers*	Number of molecules	1
	Total formula weight	172.2
All*	Total formula weight	32694.6

*Water molecules are not included.