6ID4
Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A*11:01
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, E) | MHC class I antigen | polymer | 276 | 31986.3 | 2 | UniProt (F6IQY1) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (Human) | |
| 2 | B, F (B, F) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 2 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (Human) | |
| 3 | C, G (C, H) | Heavy chain | polymer | 222 | 23629.6 | 2 | Homo sapiens | ||
| 4 | D, H (D, L) | Light chain | polymer | 221 | 23642.3 | 2 | Homo sapiens | ||
| 5 | I, J (T, U) | peptide | polymer | 9 | 1013.2 | 2 | Human immunodeficiency virus 1 | ||
| 6 | K, M, O, P, R (A, B, D, E) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 7 | L, N, Q, S, T (A, B, E, F) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 5 | Chemie (PEG) | |||
| 8 | AA, BA, CA, DA, U... (H, L, T, U, A...) | water | water | 18.0 | 803 | Chemie (HOH) |
Sequence modifications
A, E: 1 - 275 (UniProt: F6IQY1)
B, F: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 184301.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 991.1 | |
| All* | Total formula weight | 185292.4 |
