6IC7
Human cathepsin-C in complex with dipeptidyl cyclopropyl nitrile inhibitor 3
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Dipeptidyl peptidase 1 | polymer | 119 | 13500.2 | 1 | UniProt (P53634) Pfam (PF08773) In PDB | Homo sapiens (Human) | Cathepsin C,Cathepsin J,Dipeptidyl peptidase I,DPPI,Dipeptidyl transferase |
2 | B | Dipeptidyl peptidase 1 | polymer | 162 | 18302.6 | 1 | UniProt (P53634) Pfam (PF00112) In PDB | Homo sapiens (Human) | Cathepsin C,Cathepsin J,Dipeptidyl peptidase I,DPPI,Dipeptidyl transferase |
3 | C | Dipeptidyl peptidase 1 | polymer | 69 | 7583.4 | 1 | UniProt (P53634) In PDB | Homo sapiens (Human) | Cathepsin C,Cathepsin J,Dipeptidyl peptidase I,DPPI,Dipeptidyl transferase |
4 | D | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G42227JK) | |||
5 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
6 | B | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
7 | B | 1-azanyl-~{N}-[(1~{R},2~{R})-1-cyano-2-[4-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]phenyl]cyclopropyl]cyclohexane-1-carboxamide | non-polymer | 521.7 | 1 | Chemie (H9H) | |||
8 | water | water | 18.0 | 349 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 39386.2 | |
Branched | Number of molecules | 1 |
Total formula weight | 910.8 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 999.5 | |
All* | Total formula weight | 41296.6 |