6I6V
SEPIAPTERIN REDUCTASE IN COMPLEX WITH COMPOUND 6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Sepiapterin reductase | polymer | 276 | 29948.5 | 2 | UniProt (P35270) Pfam (PF00106) | Homo sapiens (Human) | SPR |
| 2 | C, H (A, B) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) PubChem (4412) PubChem (46936685) PubChem (90473931) PubChem (91972139) PubChem (145946263) PubChem (153311489) PubChem (174001641) PubChem (71717786) PubChem (5885) PubChem (165382010) | |||
| 3 | D, I (A, B) | 2-[[(3~{R})-oxan-3-yl]methylsulfonyl]-2-azaspiro[4.5]decane | non-polymer | 301.4 | 2 | Chemie (H6E) PubChem (75511445) PubChem (97841189) PubChem (97841190) | |||
| 4 | E, F, G, J, K... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 5 | M, N (A, B) | water | water | 18.0 | 446 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 261 (UniProt: P35270)
| PDB | External Database | Details |
|---|---|---|
| Met -14 | - | initiating methionine |
| Gly -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| His -9 | - | expression tag |
| His -8 | - | expression tag |
| His -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Asn -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Tyr -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Gln -1 | - | expression tag |
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 59896.9 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2462.1 | |
| All* | Total formula weight | 62359.0 |
