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6I58

Allosteric activation of human prekallikrein by apple domain disc rotation

Replaces:  2F83
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Coagulation factor XIpolymer60768116.61UniProt (P03951)
Pfam (PF00024)
Pfam (PF00089)
Homo sapiens (Human)FXI,Plasma thromboplastin antecedent,PTA
2B
(B)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.41In PDB
GlyTouCan (G42666HT)
3C, D, E, F, G
(A)
CHLORIDE IONnon-polymer35.55Chemie (CL)
4H
(A)
DI(HYDROXYETHYL)ETHERnon-polymer106.11Chemie (PEG)
5I, J
(A)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
6K
(A)
waterwater18.083Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight68116.6
BranchedNumber of molecules1
Total formula weight424.4
Non-Polymers*Number of molecules8
Total formula weight725.8
All*Total formula weight69266.8
*Water molecules are not included.

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PDB entries from 2025-07-16

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