6I4Q

Crystal structure of the human dihydrolipoamide dehydrogenase at 1.75 Angstrom resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Dihydrolipoyl dehydrogenase, mitochondrial	polymer	496	52637.2	2	UniProt (P09622) Pfam (PF07992) Pfam (PF02852) In PDB	Homo sapiens (Human)	Dihydrolipoamide dehydrogenase,Glycine cleavage system L protein
2	A, B	FLAVIN-ADENINE DINUCLEOTIDE	non-polymer		785.5	2	Chemie (FAD)
3	A, B	2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		209.2	2	Chemie (BTB)
4	A, B	SULFATE ION	non-polymer		96.1	10	Chemie (SO4)
5		water	water		18.0	537	Chemie (HOH)

Sequence modifications

A, B: 1 - 474 (UniProt: P09622)

PDB	External Database	Details
Met -21	-	initiating methionine
Ala -20	-	expression tag
Ser -19	-	expression tag
Trp -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
Pro -15	-	expression tag
Gln -14	-	expression tag
Phe -13	-	expression tag
Glu -12	-	expression tag
Lys -11	-	expression tag
Gly -10	-	expression tag
Ala -9	-	expression tag
Leu -8	-	expression tag
Glu -7	-	expression tag
Val -6	-	expression tag
Leu -5	-	expression tag
Phe -4	-	expression tag
Gln -3	-	expression tag
Gly -2	-	expression tag
Pro -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	105274.3
Non-Polymers*	Number of molecules	14
	Total formula weight	2950.2
All*	Total formula weight	108224.6

*Water molecules are not included.