6I4K
Crystal Structure of Plasmodium falciparum actin I (G115A mutant) in the Ca-ATP state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Actin-1 | polymer | 378 | 42061.7 | 1 | UniProt (Q8I4X0) Pfam (PF00022) | Plasmodium falciparum (isolate 3D7) | Actin I |
| 2 | B (G) | Gelsolin | polymer | 127 | 14211.9 | 1 | UniProt (P13020) Pfam (PF00626) | Mus musculus (Mouse) | Actin-depolymerizing factor,ADF,Brevin |
| 3 | C (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 4 | D, I, J (A, G) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 5 | E, K (A, G) | THIOCYANATE ION | non-polymer | 58.1 | 2 | Chemie (SCN) | |||
| 6 | F (A) | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 209.2 | 1 | Chemie (BTB) | |||
| 7 | G (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 8 | H (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 9 | L (G) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 1 | Chemie (BME) | |||
| 10 | M, N (A, G) | water | water | 18.0 | 517 | Chemie (HOH) |
Sequence modifications
A: 1 - 376 (UniProt: Q8I4X0)
G: 1 - 125 (UniProt: P13020)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Ala 115 | Gly 115 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 56273.6 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1172.5 | |
| All* | Total formula weight | 57446.2 |
