6I4J

Crystal Structure of Plasmodium falciparum actin I (F54Y mutant) in the Mg-ADP state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Actin-1	polymer	378	42063.7	1	UniProt (Q8I4X0) Pfam (PF00022) In PDB	Plasmodium falciparum (isolate 3D7)	Actin I
2	G	Gelsolin	polymer	127	14211.9	1	UniProt (P13020) Pfam (PF00626) In PDB	Mus musculus (Mouse)	Actin-depolymerizing factor,ADF,Brevin
3	A	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (ADP)
4	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
5	A, G	THIOCYANATE ION	non-polymer		58.1	5	Chemie (SCN)
6	A	2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		209.2	1	Chemie (BTB)
7	A	POTASSIUM ION	non-polymer		39.1	1	Chemie (K)
8	G	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
9		water	water		18.0	513	Chemie (HOH)

Sequence modifications

A: 1 - 376 (UniProt: Q8I4X0)

PDB	External Database	Details
Gly -1	-	expression tag
Ala 0	-	expression tag
Tyr 54	Phe 54	engineered mutation

G: 1 - 125 (UniProt: P13020)

PDB	External Database	Details
Gly -1	-	expression tag
Pro 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	56275.6
Non-Polymers*	Number of molecules	11
	Total formula weight	1070.4
All*	Total formula weight	57346.0

*Water molecules are not included.