6I4G
Crystal Structure of Plasmodium falciparum actin I (H74Q) in the Mg-K-ATP state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Actin-1 | polymer | 378 | 42037.7 | 2 | UniProt (Q8I4X0) Pfam (PF00022) | Plasmodium falciparum (isolate 3D7) | Actin I |
| 2 | C, D (G, H) | Gelsolin | polymer | 127 | 14211.9 | 2 | UniProt (P13020) Pfam (PF00626) | Mus musculus (Mouse) | Actin-depolymerizing factor,ADF,Brevin |
| 3 | E, H (A, B) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
| 4 | F, I (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | G, J (A, B) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 6 | K, N, R (B, G, H) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 3 | Chemie (BME) | |||
| 7 | L, M, P, Q (G, H) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 8 | O (G) | THIOCYANATE ION | non-polymer | 58.1 | 1 | Chemie (SCN) | |||
| 9 | S, T, U, V (A, B, G, H) | water | water | 18.0 | 399 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 376 (UniProt: Q8I4X0)
G, H: 1 - 125 (UniProt: P13020)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Gln 74 | His 74 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 112499.2 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1594.0 | |
| All* | Total formula weight | 114093.1 |
