6I4F
Crystal Structure of Plasmodium falciparum actin I (A272W mutant) in the Mg-K-ATP/ADP state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Actin-1 | polymer | 378 | 42162.8 | 1 | UniProt (Q8I4X0) Pfam (PF00022) | Plasmodium falciparum (isolate 3D7) | Actin I |
| 2 | B (G) | Gelsolin | polymer | 127 | 14211.9 | 1 | UniProt (P13020) Pfam (PF00626) | Mus musculus (Mouse) | Actin-depolymerizing factor,ADF,Brevin |
| 3 | C (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 4 | D (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 5 | E (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | F (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 7 | G (A) | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 209.2 | 1 | Chemie (BTB) | |||
| 8 | H (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 9 | I (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 10 | J (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 11 | K, L (G) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 12 | M, N (A, G) | water | water | 18.0 | 517 | Chemie (HOH) |
Sequence modifications
A: 1 - 376 (UniProt: Q8I4X0)
G: 1 - 125 (UniProt: P13020)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Trp 272 | Ala 272 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 56374.7 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1451.7 | |
| All* | Total formula weight | 57826.5 |
