6I4E

Crystal Structure of Plasmodium falciparum actin I in the Mg-ADP state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Actin-1	polymer	378	42047.7	1	UniProt (Q8I4X0) Pfam (PF00022) In PDB	Plasmodium falciparum (isolate 3D7)	Actin I
2	G	Gelsolin	polymer	127	14211.9	1	UniProt (P13020) Pfam (PF00626) In PDB	Mus musculus (Mouse)	Actin-depolymerizing factor,ADF,Brevin
3	A	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (ADP)
4	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
5	A, G	CALCIUM ION	non-polymer		40.1	3	Chemie (CA)
6	A	THIOCYANATE ION	non-polymer		58.1	2	Chemie (SCN)
7	A	BETA-MERCAPTOETHANOL	non-polymer		78.1	2	Chemie (BME)
8	A	2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		209.2	1	Chemie (BTB)
9	G	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
10		water	water		18.0	445	Chemie (HOH)

Sequence modifications

A: 1 - 376 (UniProt: Q8I4X0)

PDB	External Database	Details
Gly -1	-	expression tag
Ala 0	-	expression tag

G: 1 - 125 (UniProt: P13020)

PDB	External Database	Details
Gly -1	-	expression tag
Pro 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	56259.6
Non-Polymers*	Number of molecules	11
	Total formula weight	1159.5
All*	Total formula weight	57419.1

*Water molecules are not included.