6I48
Structure of P. aeruginosa LpxC with compound 12: (2R)-4-(6-(2-Fluoro-4-methoxyphenyl)-3-oxo-1H-pyrrolo[1,2-c]imidazol-2(3H)-yl)-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (AAA) | UDP-3-O-acyl-N-acetylglucosamine deacetylase | polymer | 299 | 33146.6 | 1 | UniProt (B7UZI4) Pfam (PF03331) | Pseudomonas aeruginosa LESB58 | UDP-3-O-acyl-GlcNAc deacetylase,UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase |
| 2 | B (AAA) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (AAA) | (2~{R})-4-[6-(2-fluoranyl-4-methoxy-phenyl)-3-oxidanylidene-1~{H}-pyrrolo[1,2-c]imidazol-2-yl]-2-methyl-2-methylsulfonyl-~{N}-oxidanyl-butanamide | non-polymer | 439.5 | 1 | Chemie (H2H) | |||
| 4 | D (AAA) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | E (AAA) | water | water | 18.0 | 9 | Chemie (HOH) |
Sequence modifications
AAA: 1 - 299 (UniProt: B7UZI4)
| PDB | External Database | Details |
|---|---|---|
| Ser 40 | Cys 40 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33146.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 566.9 | |
| All* | Total formula weight | 33713.6 |
