6I35
Crystal structure of human glycine decarboxylase (P-protein) bound with pyridoxyl-glycine-5'-monophosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Glycine dehydrogenase (decarboxylating), mitochondrial | polymer | 984 | 109512.2 | 4 | UniProt (P23378) Pfam (PF02347) Pfam (PF01212) Pfam (PF21478) | Homo sapiens (Human) | Glycine cleavage system P protein,Glycine decarboxylase,Glycine dehydrogenase (aminomethyl-transferring) |
| 2 | E, L, N, T (A, B, C, D) | N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE] | non-polymer | 306.2 | 4 | Chemie (PLG) | |||
| 3 | F, J, O, U (A, B, C, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 4 | G, H, M, P, R (A, B, C) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 5 | I (A) | BICARBONATE ION | non-polymer | 61.0 | 1 | Chemie (BCT) | |||
| 6 | K, Q, S, V (B, C, D) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 4 | Chemie (PEG) | |||
| 7 | W, X, Y, Z (A, B, C, D) | water | water | 18.0 | 1024 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 45 - 1020 (UniProt: P23378)
| PDB | External Database | Details |
|---|---|---|
| Met 44 | - | initiating methionine |
| Gly 1021 | - | expression tag |
| His 1022 | - | expression tag |
| His 1023 | - | expression tag |
| His 1024 | - | expression tag |
| His 1025 | - | expression tag |
| His 1026 | - | expression tag |
| His 1027 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 438048.8 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 2419.1 | |
| All* | Total formula weight | 440467.9 |
