6I2U
Aurora-A kinase domain in complex with Coenzyme A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Aurora kinase A | polymer | 285 | 33108.7 | 1 | UniProt (O14965) Pfam (PF00069) | Homo sapiens (Human) | Aurora 2,Aurora/IPL1-related kinase 1,hARK1,Breast tumor-amplified kinase,Serine/threonine-protein kinase 15,Serine/threonine-protein kinase 6,Serine/threonine-protein kinase aurora-A |
| 2 | B (A) | COENZYME A | non-polymer | 767.5 | 1 | Chemie (COA) | |||
| 3 | C, D, E, F (A) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | G, H, I (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 5 | J (A) | water | water | 18.0 | 26 | Chemie (HOH) |
Sequence modifications
A: 122 - 403 (UniProt: O14965)
| PDB | External Database | Details |
|---|---|---|
| Gly 119 | - | expression tag |
| Ala 120 | - | expression tag |
| Met 121 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33108.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1183.1 | |
| All* | Total formula weight | 34291.9 |
