6I1H

Crystal structure of TP domain from Chlamydia trachomatis Penicillin-Binding Protein 3 in complex with meropenem

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Penicillin-binding protein,Penicillin-binding protein	polymer	346	36467.8	2	UniProt (A0A0E9FXJ8)	Chlamydia trachomatis
2	C, D (A, B)	(4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-d ihydro-1H-pyrrole-2-carboxylic acid	non-polymer		385.5	2	Chemie (MER)
3	E, F (A, B)	water	water		18.0	178	Chemie (HOH)

Sequence modifications

A, B: 263 - 305 (UniProt: A0A0E9FXJ8)

PDB	External Database	Details
Gly 256	-	expression tag
Pro 257	-	expression tag
Gly 258	-	expression tag
Tyr 259	-	expression tag
Gln 260	-	expression tag
Asp 261	-	expression tag
Pro 262	-	expression tag

A, B: 308 - 601 (UniProt: A0A0E9FXJ8)

PDB	External Database	Details
Pro 306	-	linker
Gly 307	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	72935.6
Non-Polymers*	Number of molecules	2
	Total formula weight	771.0
All*	Total formula weight	73706.5

*Water molecules are not included.