6I0R
Structure of quinolinate synthase in complex with 5-mercaptopyridine-2,3-dicarboxylic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Quinolinate synthase A | polymer | 305 | 34640.6 | 1 | UniProt (Q9X1X7) Pfam (PF02445) In PDB | Thermotoga maritima MSB8 | |
| 2 | A | FE (III) ION | non-polymer | 55.8 | 4 | Chemie (FE) | |||
| 3 | A | HYDROSULFURIC ACID | non-polymer | 34.1 | 4 | Chemie (H2S) | |||
| 4 | A | 5-mercaptopyridine-2,3-dicarboxylic acid | non-polymer | 199.2 | 1 | Chemie (QAT) | |||
| 5 | water | water | 18.0 | 110 | Chemie (HOH) |
Sequence modifications
A: 1 - 298 (UniProt: Q9X1X7)
| PDB | External Database | Details |
|---|---|---|
| Met -6 | - | initiating methionine |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| Phe 21 | Tyr 21 | engineered mutation |
| Arg 219 | Lys 219 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34640.6 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 558.9 | |
| All* | Total formula weight | 35199.5 |
