6I0L
Crystal structure of human carbonic anhydrase I in complex with the 1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-(4-sulfamoylphenyl)ethyl]urea inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Carbonic anhydrase 1 | polymer | 261 | 28906.2 | 2 | UniProt (P00915) Pfam (PF00194) In PDB | Homo sapiens (Human) | Carbonate dehydratase I,Carbonic anhydrase B,CAB,Carbonic anhydrase I,CA-I |
| 2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | A, B | 1-[4-chloranyl-3-(trifluoromethyl)phenyl]-3-[2-(4-sulfamoylphenyl)ethyl]urea | non-polymer | 421.8 | 2 | Chemie (GZH) | |||
| 4 | A, B | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | A | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 6 | water | water | 18.0 | 504 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 57812.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1309.8 | |
| All* | Total formula weight | 59122.2 |
