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6HYS

Crystal structure of DHX8 helicase domain bound to ADP at 2.6 angstrom

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
ATP-dependent RNA helicase DHX8polymer67376822.64UniProt (Q14562)
Pfam (PF00270)
Pfam (PF00271)
Pfam (PF04408)
Pfam (PF21010)
Pfam (PF07717)
Homo sapiens (Human)DEAH box protein 8,RNA helicase HRH1
2DA, E, PA, R
(C, A, D, B)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.24Chemie (ADP)
3EA, F, QA, S
(C, A, D, B)
MAGNESIUM IONnon-polymer24.34Chemie (MG)
4AA, BA, CA, G, GA...
(B, A, C, D)
DIMETHYL SULFOXIDEnon-polymer78.132Chemie (DMS)
5FA, H, I, RA, SA...
(C, A, D, B)
1,2-ETHANEDIOLnon-polymer62.16Chemie (EDO)
6AB, L, Z
(D, A, B)
ACETATE IONnon-polymer59.03Chemie (ACT)
7BB, CB, DB, EB
(A, B, C, D)
waterwater18.0447Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight307290.2
Non-Polymers*Number of molecules49
Total formula weight4855.8
All*Total formula weight312146.1
*Water molecules are not included.

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PDB entries from 2025-12-17

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