6HXS

Human PARP16 (ARTD15) IN COMPLEX WITH CARBA-NAD

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Mono [ADP-ribose] polymerase PARP16	polymer	298	33582.2	3	UniProt (Q8N5Y8) Pfam (PF18084) Pfam (PF00644) In PDB	Homo sapiens (Human)	ADP-ribosyltransferase diphtheria toxin-like 15,Poly [ADP-ribose] polymerase 16,PARP-16
2	A, B	CARBA-NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		662.5	2	Chemie (CNA)
3	A, B	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
4	A	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5	C	ADENOSINE	non-polymer		267.2	1	Chemie (ADN)
6		water	water		18.0	215	Chemie (HOH)

Sequence modifications

A, B, C: 5 - 279 (UniProt: Q8N5Y8)

PDB	External Database	Details
Met -18	-	initiating methionine
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
Ser -11	-	expression tag
Ser -10	-	expression tag
Gly -9	-	expression tag
Val -8	-	expression tag
Asp -7	-	expression tag
Leu -6	-	expression tag
Gly -5	-	expression tag
Thr -4	-	expression tag
Glu -3	-	expression tag
Asn -2	-	expression tag
Leu -1	-	expression tag
Tyr 0	-	expression tag
Phe 1	-	expression tag
Gln 2	-	expression tag
Ser 3	-	expression tag
Met 4	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	100746.7
Non-Polymers*	Number of molecules	6
	Total formula weight	1876.4
All*	Total formula weight	102623.1

*Water molecules are not included.