6HXK
Structure of the citryl-CoA lyase core module of human ATP citrate lyase in complex with citrate
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | ATP-citrate synthase | polymer | 270 | 30008.0 | 4 | UniProt (P53396) Pfam (PF00285) In PDB | Homo sapiens (Human) | ATP-citrate (pro-S-)-lyase,ACL,Citrate cleavage enzyme |
2 | A, B, C, D | CITRATE ANION | non-polymer | 189.1 | 4 | Chemie (FLC) | |||
3 | A, D | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
4 | B, D | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 2 | Chemie (PGE) | |||
5 | C | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 1 | Chemie (1PE) | |||
6 | C | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
7 | water | water | 18.0 | 593 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 836 - 1101 (UniProt: P53396)
PDB | External Database | Details |
---|---|---|
Gly 832 | - | expression tag |
Ser 833 | - | expression tag |
His 834 | - | expression tag |
Met 835 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 120032.1 | |
Non-Polymers* | Number of molecules | 11 |
Total formula weight | 1587.3 | |
All* | Total formula weight | 121619.4 |