6HWM
Structure of Thermus thermophilus ClpP in complex with bortezomib
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | ATP-dependent Clp protease proteolytic subunit | polymer | 204 | 22763.1 | 7 | UniProt (Q5SKM8) Pfam (PF00574) In PDB | Thermus thermophilus | Endopeptidase Clp |
2 | A, B, C, D, E... | N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE | non-polymer | 384.2 | 7 | Chemie (BO2) | |||
3 | C, E, G | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) |
Sequence modifications
A, B, C, D, E, F, G: 1 - 194 (UniProt: Q5SKM8)
PDB | External Database | Details |
---|---|---|
Leu 195 | - | expression tag |
Glu 196 | - | expression tag |
His 197 | - | expression tag |
His 198 | - | expression tag |
His 199 | - | expression tag |
His 200 | - | expression tag |
His 201 | - | expression tag |
His 202 | - | expression tag |
His 203 | - | expression tag |
His 204 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 7 |
Total formula weight | 159341.7 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 3008.0 | |
All* | Total formula weight | 162349.8 |