6HVI
Human PFKFB3 in complex with a N-Aryl 6-Aminoquinoxaline inhibitor 2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | polymer | 520 | 59694.1 | 1 | UniProt (Q16875) Pfam (PF01591) Pfam (PF00300) | Homo sapiens (Human) | PFK/FBPase 3,6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme,Renal carcinoma antigen NY-REN-56,iPFK-2 |
| 2 | B (A) | 8-[3-(dimethylamino)phenyl]-~{N}-(4-methylsulfonylpyridin-3-yl)quinoxalin-6-amine | non-polymer | 419.5 | 1 | Chemie (GV5) | |||
| 3 | C (A) | PYROPHOSPHATE 2- | non-polymer | 176.0 | 1 | Chemie (POP) | |||
| 4 | D (A) | 6-O-phosphono-beta-D-fructofuranose | non-polymer | 260.1 | 1 | Chemie (F6P) | |||
| 5 | E (A) | CITRATE ANION | non-polymer | 189.1 | 1 | Chemie (FLC) | |||
| 6 | F (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 7 | G (A) | water | water | 18.0 | 373 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 59694.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1122.8 | |
| All* | Total formula weight | 60817.0 |
