6HV9

S. cerevisiae CMG-Pol epsilon-DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (3)	DNA replication licensing factor MCM3	polymer	971	107653.5	1	UniProt (P24279) Pfam (PF22207) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855)	Saccharomyces cerevisiae (baker's yeast)	Minichromosome maintenance protein 3
2	B (4)	DNA replication licensing factor MCM4	polymer	933	105138.4	1	UniProt (P30665) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) Pfam (PF21128)	Saccharomyces cerevisiae (baker's yeast)	Cell division control protein 54
3	C (5)	DNA replication licensing factor MCM5	polymer	775	86505.7	1	UniProt (A0A6A5PUY8) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) Pfam (PF21933) UniProt (by SIFTS) (P29496)	Saccharomyces cerevisiae (baker's yeast)
4	D (6)	DNA replication licensing factor MCM6	polymer	1017	113110.2	1	UniProt (P53091) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) Pfam (PF18263)	Saccharomyces cerevisiae (baker's yeast)	Minichromosome maintenance protein 6
5	E (2)	DNA replication licensing factor MCM2	polymer	868	98911.5	1	UniProt (A0A6A5Q1S9) Pfam (PF12619) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) UniProt (by SIFTS) (P29469)	Saccharomyces cerevisiae (baker's yeast)	Minichromosome maintenance protein 2
6	F (7)	DNA replication licensing factor MCM7	polymer	845	95049.9	1	UniProt (P38132) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855)	Saccharomyces cerevisiae (baker's yeast)	Cell division control protein 47,Minichromosome maintenance protein 7
7	G (C)	DNA replication complex GINS protein PSF1	polymer	208	24230.6	1	UniProt (A0A6A5Q203) Pfam (PF05916) UniProt (by SIFTS) (Q12488)	Saccharomyces cerevisiae (baker's yeast)
8	H (D)	DNA replication complex GINS protein PSF2	polymer	213	25096.8	1	UniProt (A0A6A5PX40) Pfam (PF05916) UniProt (by SIFTS) (P40359)	Saccharomyces cerevisiae (baker's yeast)
9	I (E)	DNA replication complex GINS protein PSF3	polymer	194	21977.1	1	UniProt (A0A8H4BWH3) Pfam (PF22466) Pfam (PF05916) UniProt (by SIFTS) (Q12146)	Saccharomyces cerevisiae (baker's yeast)
10	J (F)	DNA replication complex GINS protein SLD5	polymer	294	33983.6	1	UniProt (Q03406) Pfam (PF05916) Pfam (PF16922)	Saccharomyces cerevisiae (baker's yeast)
11	K (G)	Cell division control protein 45	polymer	650	74324.8	1	UniProt (Q08032) Pfam (PF02724)	Saccharomyces cerevisiae (baker's yeast)
12	L (X)	DNA (5'-D(*GP*CP*AP*GP*CP*CP*AP*CP*GP*CP*TP*GP*GP*CP*CP*GP*TP*TP*TP*TP*A)-3')	polymer	21	6415.1	1		Saccharomyces cerevisiae
13	M (Y)	DNA (5'-D(P*TP*AP*AP*AP*AP*CP*GP*GP*CP*CP*AP*GP*CP*GP*TP*GP*GP*CP*TP*GP*C)-3')	polymer	21	6473.2	1		Saccharomyces cerevisiae
14	N (J)	DNA (5'-D(P*TP*TP*TP*TP*TP*TP*T)-3')	polymer	7	2084.4	1		Saccharomyces cerevisiae
15	O (B)	DNA polymerase epsilon subunit B	polymer	689	78408.8	1	UniProt (P24482) Pfam (PF04042)	Saccharomyces cerevisiae	DNA polymerase II subunit 2
16	P (A)	DNA polymerase epsilon catalytic subunit	polymer	914	104984.8	1	UniProt (A0A8H4BWE7) Pfam (PF08490) Pfam (PF22912) UniProt (by SIFTS) (P21951)	Saccharomyces cerevisiae (baker's yeast)
17	Q, R (5)	PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER	non-polymer		523.2	2	Chemie (AGS)
18	S, T (A)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)

Sequence modifications

B: 1 - 689 (UniProt: P24482)

PDB	External Database	Details
Asn 266	Met 266	conflict

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	984348.5
Non-Polymers*	Number of molecules	4
	Total formula weight	1177.3
All*	Total formula weight	985525.8

*Water molecules are not included.