6HUZ

HmdII from Desulfurobacterium thermolithotrophum reconstituted with Fe-guanylylpyridinol (FeGP) cofactor and co-crystallized with methenyl-tetrahydrofolate form B

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase-related protein	polymer	370	40994.0	1	UniProt (F0S2B6) Pfam (PF22616) Pfam (PF03201)	Desulfurobacterium thermolithotrophum DSM 11699
2	B (A)	iron-guanylyl pyridinol cofactor	non-polymer		686.3	1	Chemie (FE9)
3	C (A)	5,10-Methenyltetrahydrofolate	non-polymer		456.4	1	Chemie (GUE)
4	D, E (A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
5	F (A)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
6	G, H, I (A)	SODIUM ION	non-polymer		23.0	3	Chemie (NA)
7	J (A)	water	water		18.0	281	Chemie (HOH)

Sequence modifications

A: 1 - 357 (UniProt: F0S2B6)

PDB	External Database	Details
Lys 358	-	expression tag
Leu 359	-	expression tag
Ala 360	-	expression tag
Ala 361	-	expression tag
Ala 362	-	expression tag
Leu 363	-	expression tag
Glu 364	-	expression tag
His 365	-	expression tag
His 366	-	expression tag
His 367	-	expression tag
His 368	-	expression tag
His 369	-	expression tag
His 370	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	40994.0
Non-Polymers*	Number of molecules	8
	Total formula weight	1458.0
All*	Total formula weight	42452.0

*Water molecules are not included.