6HUX
HmdII from Methanocaldococcus jannaschii reconstitued with Fe-guanylylpyridinol (FeGP) cofactor and co-crystallized with methenyl-tetrahydromethanopterin at 2.5 A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338 | polymer | 375 | 40663.8 | 1 | UniProt (Q58734) Pfam (PF03201) In PDB | Methanocaldococcus jannaschii DSM 2661 (Methanococcus jannaschii) | |
| 2 | A | ACETATE ION | non-polymer | 59.0 | 9 | Chemie (ACT) | |||
| 3 | A | iron-guanylyl pyridinol cofactor | non-polymer | 686.3 | 1 | Chemie (FE9) | |||
| 4 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | A | 1-{4-[(6S,6aR,7R)-3-amino-6,7-dimethyl-1-oxo-1,2,5,6,6a,7-hexahydro-8H-imidazo[1,5-f]pteridin-10-ium-8-yl]phenyl}-1-deoxy-5-O-{5-O-[(S)-{[(1S)-1,3-dicarboxypropyl]oxy}(hydroxy)phosphoryl]-alpha-D-ribofuranosyl}-D-ribitol | non-polymer | 787.7 | 1 | Chemie (E4M) | |||
| 6 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 7 | A | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
| 8 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 9 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 10 | water | water | 18.0 | 53 | Chemie (HOH) |
Sequence modifications
A: 1 - 353 (UniProt: Q58734)
| PDB | External Database | Details |
|---|---|---|
| Ala 354 | - | expression tag |
| Asp 355 | - | expression tag |
| Pro 356 | - | expression tag |
| Asn 357 | - | expression tag |
| Ser 358 | - | expression tag |
| Ser 359 | - | expression tag |
| Ser 360 | - | expression tag |
| Val 361 | - | expression tag |
| Asp 362 | - | expression tag |
| Lys 363 | - | expression tag |
| Leu 364 | - | expression tag |
| Ala 365 | - | expression tag |
| Ala 366 | - | expression tag |
| Ala 367 | - | expression tag |
| Leu 368 | - | expression tag |
| Glu 369 | - | expression tag |
| His 370 | - | expression tag |
| His 371 | - | expression tag |
| His 372 | - | expression tag |
| His 373 | - | expression tag |
| His 374 | - | expression tag |
| His 375 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40663.8 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 2946.8 | |
| All* | Total formula weight | 43610.6 |
