6HT0
Crystal structure of MLLT1 (ENL) YEATS domain in complexed with compound 94
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Protein ENL | polymer | 155 | 18312.1 | 1 | UniProt (Q03111) Pfam (PF03366) In PDB | Homo sapiens (Human) | YEATS domain-containing protein 1 |
| 2 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 4 | A | 1-cyclopropyl-~{N}-[2-[[(2~{S})-2-methylpyrrolidin-1-yl]methyl]-3~{H}-benzimidazol-5-yl]indazole-5-carboxamide | non-polymer | 414.5 | 1 | Chemie (GQ8) | |||
| 5 | water | water | 18.0 | 85 | Chemie (HOH) |
Sequence modifications
A: 1 - 148 (UniProt: Q03111)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| His 149 | - | expression tag |
| His 150 | - | expression tag |
| His 151 | - | expression tag |
| His 152 | - | expression tag |
| His 153 | - | expression tag |
| His 154 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18312.1 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1007.1 | |
| All* | Total formula weight | 19319.2 |
