6HSN
Crystal structure of the ternary complex of GephE-ADP-GABA(A) receptor derived peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Gephyrin | polymer | 419 | 45652.4 | 1 | UniProt (Q03555) Pfam (PF03453) Pfam (PF00994) Pfam (PF03454) | Rattus norvegicus (Rat) | Putative glycine receptor-tubulin linker protein |
| 2 | B, C (D, E) | Gamma-aminobutyric acid receptor subunit alpha-3 | polymer | 10 | 1114.3 | 2 | UniProt (P20236) | Rattus norvegicus | GABA(A) receptor subunit alpha-3 |
| 3 | D (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 4 | E, F (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | G, H, I (A) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 3 | Chemie (MPD) | |||
| 6 | J, K, L, M, N... (A) | ACETATE ION | non-polymer | 59.0 | 8 | Chemie (ACT) | |||
| 7 | R (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 8 | S (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 9 | T (D) | 1,1'-[ethane-1,2-diylbis(oxyethane-2,1-diyl)]bis(1H-pyrrole-2,5-dione) | non-polymer | 308.3 | 1 | Chemie (3F8) | |||
| 10 | U, V, W (A, D, E) | water | water | 18.0 | 480 | Chemie (HOH) |
Sequence modifications
D, E: 368 - 377 (UniProt: P20236)
| PDB | External Database | Details |
|---|---|---|
| Cys 377 | Ile 405 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 47880.9 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 1728.9 | |
| All* | Total formula weight | 49609.9 |
