6HMX
RIP2 Kinase Catalytic Domain complex with N(4,5dimethyl1Hpyrazol3yl)7methoxy6(2methylpropane2sulfonyl)quinolin4amine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Receptor-interacting serine/threonine-protein kinase 2 | polymer | 311 | 35683.0 | 2 | UniProt (O43353) Pfam (PF07714) In PDB | Homo sapiens (Human) | CARD-containing interleukin-1 beta-converting enzyme-associated kinase,CARD-containing IL-1 beta ICE-kinase,RIP-like-interacting CLARP kinase,Receptor-interacting protein 2,RIP-2,Tyrosine-protein kinase RIPK2 |
| 2 | A, B | 6-~{tert}-butylsulfonyl-~{N}-(3,4-dimethyl-1~{H}-pyrazol-5-yl)-7-methoxy-quinolin-4-amine | non-polymer | 388.5 | 2 | Chemie (GEZ) | |||
| 3 | water | water | 18.0 | 310 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 310 (UniProt: O43353)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71366.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 777.0 | |
| All* | Total formula weight | 72142.9 |
