6HMO

Solution structure of the RNA duplex formed by the 5'-end of U1snRNA and the 5'-splice site of SMN2 exon7 in complex with the SMN-C5 splicing modifier

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	RNA (5'-R(*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3')	polymer	11	3428.1	1		Homo sapiens
2	B (B)	RNA (5'-R(*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3')	polymer	11	3547.2	1		Homo sapiens
3	C (A)	2-(8-fluoranyl-2-methyl-imidazo[1,2-a]pyridin-6-yl)-7-(4-methylpiperazin-1-yl)pyrido[1,2-a]pyrimidin-4-one	non-polymer		392.4	1	Chemie (GDZ)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	6975.2
Non-Polymers*	Number of molecules	1
	Total formula weight	392.4
All*	Total formula weight	7367.7

*Water molecules are not included.