6HM6
CRYSTAL STRUCTURE OF SPLEEN TYROSINE KINASE (SYK) IN COMPLEX WITH A 2-(PYRIDINYLOXYMETHYL)PYRIDINE INHIBITOR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SPLEEN TYROSINE KINASE | polymer | 276 | 32104.9 | 1 | UniProt (P43405) Pfam (PF07714) | Homo sapiens (Human) | |
| 2 | B (A) | 2-(4-methylphenyl)-3-(pyridin-2-ylmethoxy)pyridine | non-polymer | 276.3 | 1 | Chemie (GDK) | |||
| 3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | D (A) | water | water | 18.0 | 119 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32104.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 368.4 | |
| All* | Total formula weight | 32473.4 |
