6HL6
Factor Inhibiting HIF (FIH) in complex with zinc, NOG and iASPP(670-693)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Hypoxia-inducible factor 1-alpha inhibitor | polymer | 350 | 40415.4 | 1 | UniProt (Q9NWT6) Pfam (PF13621) | Homo sapiens (Human) | Factor inhibiting HIF-1,FIH-1,Hypoxia-inducible factor asparagine hydroxylase |
| 2 | B (S) | RelA-associated inhibitor | polymer | 24 | 2420.6 | 1 | UniProt (Q8WUF5) | Homo sapiens | Inhibitor of ASPP protein,Protein iASPP,NFkB-interacting protein 1,PPP1R13B-like protein |
| 3 | C, D, E, F, G (A) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 4 | H, I, J (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 5 | K (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 6 | L (A) | N-OXALYLGLYCINE | non-polymer | 147.1 | 1 | Chemie (OGA) | |||
| 7 | M, N (A, S) | water | water | 18.0 | 234 | Chemie (HOH) |
Sequence modifications
A: 1 - 349 (UniProt: Q9NWT6)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42835.9 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 961.2 | |
| All* | Total formula weight | 43797.1 |
