6HKM
Crystal structure of Compound 1 with ERK5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase 7 | polymer | 347 | 39725.8 | 1 | UniProt (Q13164) Pfam (PF00069) | Homo sapiens (Human) | MAPK 7,Big MAP kinase 1,BMK-1,Extracellular signal-regulated kinase 5,ERK-5 |
| 2 | B (A) | [4-(6,7-dimethoxyquinazolin-4-yl)piperidin-1-yl]-[4-(trifluoromethyloxy)phenyl]methanone | non-polymer | 461.4 | 1 | Chemie (G92) | |||
| 3 | C (A) | water | water | 18.0 | 33 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39725.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 461.4 | |
| All* | Total formula weight | 40187.2 |
