6HJY

X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) Delta8 truncation mutant in complex with nanobody 72

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Cys-loop ligand-gated ion channel	polymer	277	32102.5	1	UniProt (P0C7B7) Pfam (PF02931) In PDB	Dickeya chrysanthemi (Pectobacterium chrysanthemi)	ELIC
2	B, C	Cys-loop ligand-gated ion channel	polymer	280	32413.8	2	UniProt (P0C7B7) Pfam (PF02931) In PDB	Dickeya chrysanthemi (Pectobacterium chrysanthemi)	ELIC
3	D	Cys-loop ligand-gated ion channel	polymer	276	32031.4	1	UniProt (P0C7B7) Pfam (PF02931) In PDB	Dickeya chrysanthemi (Pectobacterium chrysanthemi)	ELIC
4	E	Cys-loop ligand-gated ion channel	polymer	278	32217.5	1	UniProt (P0C7B7) Pfam (PF02931) In PDB	Dickeya chrysanthemi (Pectobacterium chrysanthemi)	ELIC
5	F, J	nanobody 72	polymer	124	13368.0	2		Lama glama
6	G, H, I	nanobody 72	polymer	123	13239.8	3		Lama glama

Sequence modifications

A: 9 - 285 (UniProt: P0C7B7)

PDB	External Database	Details
Gly 164	-	insertion
Cys 238	Leu 237	conflict

B, C: 8 - 285 (UniProt: P0C7B7)

PDB	External Database	Details
Pro 6	-	expression tag
Val 7	-	expression tag
Gly 164	-	insertion
Cys 238	Leu 237	conflict

D: 10 - 285 (UniProt: P0C7B7)

PDB	External Database	Details
Gly 164	-	insertion
Cys 238	Leu 237	conflict

E: 8 - 285 (UniProt: P0C7B7)

PDB	External Database	Details
Gly 164	-	insertion
Cys 238	Leu 237	conflict

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	227634.4
All*	Total formula weight	227634.4

*Water molecules are not included.