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6HGQ

Crystal Structure of Human APRT wild type in complex with Hypoxanthine, PRPP and Mg2+

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, C, D, B)
Adenine phosphoribosyltransferasepolymer17919498.54UniProt (P07741)
Pfam (PF00156)
Homo sapiens (Human)APRT
2E
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
3F, I, L, O
(A, C, D, B)
MAGNESIUM IONnon-polymer24.34Chemie (MG)
4G, J, M, P
(A, C, D, B)
1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranosenon-polymer390.14Chemie (PRP)
5H, K, N, Q
(A, C, D, B)
HYPOXANTHINEnon-polymer136.14Chemie (HPA)
6R, S, T, U
(A, C, D, B)
waterwater18.0345Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight77994.1
Non-Polymers*Number of molecules13
Total formula weight2294.0
All*Total formula weight80288.2
*Water molecules are not included.

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PDB entries from 2025-06-11

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