6HG2
Hybrid dihydroorotase domain of human CAD with E. coli flexible loop, bound to fluoroorotate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | CAD protein | polymer | 395 | 42851.9 | 1 | UniProt (P27708) Pfam (PF01979) In PDB | Homo sapiens (Human) | |
| 2 | A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | A | 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID | non-polymer | 174.1 | 1 | Chemie (FOT) | |||
| 4 | A | FORMIC ACID | non-polymer | 46.0 | 1 | Chemie (FMT) | |||
| 5 | water | water | 18.0 | 256 | Chemie (HOH) |
Sequence modifications
A: 1456 - 1846 (UniProt: P27708)
| PDB | External Database | Details |
|---|---|---|
| Gly 1454 | - | expression tag |
| Pro 1455 | - | expression tag |
| Ala 1560 | - | insertion |
| Ala 1560 | - | insertion |
| Thr 1560 | Glu 1561 | conflict |
| Asn 1560 | Phe 1563 | conflict |
| Ser 1560 | Glu 1565 | conflict |
| His 1560 | Leu 1566 | conflict |
| Gly 1567 | Arg 1567 | conflict |
| Val 1568 | Leu 1568 | conflict |
| Thr 1569 | Asp 1569 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42851.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 350.9 | |
| All* | Total formula weight | 43202.8 |
