6HFQ
Human dihydroorotase mutant F1563T co-crystallized with carbamoyl aspartate at pH 7.5
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | CAD protein | polymer | 393 | 42855.9 | 1 | UniProt (P27708) Pfam (PF01979) In PDB | Homo sapiens (Human) | |
2 | A | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
3 | A | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID | non-polymer | 158.1 | 1 | Chemie (DOR) | |||
4 | A | FORMIC ACID | non-polymer | 46.0 | 4 | Chemie (FMT) | |||
5 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
6 | water | water | 18.0 | 350 | Chemie (HOH) |
Sequence modifications
A: 1456 - 1846 (UniProt: P27708)
PDB | External Database | Details |
---|---|---|
Gly 1454 | - | expression tag |
Pro 1455 | - | expression tag |
Gly 1513 | Ala 1513 | conflict |
Thr 1563 | Phe 1563 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 42855.9 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 695.9 | |
All* | Total formula weight | 43551.9 |