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6HFH

Human dihydroorotase mutant F1563A co-crystallized with carbamoyl aspartate at pH 7.0

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ACAD proteinpolymer39342839.91UniProt (P27708)
Pfam (PF01979)
In PDB
Homo sapiens (Human)
2AZINC IONnon-polymer65.44Chemie (ZN)
3AFORMIC ACIDnon-polymer46.03Chemie (FMT)
4A(4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACIDnon-polymer158.11Chemie (DOR)
5waterwater18.0423Chemie (HOH)
Sequence modifications
A: 1456 - 1846 (UniProt: P27708)
PDBExternal DatabaseDetails
Gly 1454-expression tag
Pro 1455-expression tag
Ala 1563Phe 1563engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight42839.9
Non-Polymers*Number of molecules8
Total formula weight557.8
All*Total formula weight43397.7
*Water molecules are not included.

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PDB entries from 2024-09-04

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