6HEP
Crystal structure of human 14-3-3 beta in complex with CFTR R-domain peptide pS753-pS768
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | 14-3-3 protein beta/alpha | polymer | 235 | 26987.5 | 4 | UniProt (P31946) Pfam (PF00244) In PDB | Homo sapiens (Human) | Protein 1054,Protein kinase C inhibitor protein 1,KCIP-1 |
| 2 | E, F | Cystic fibrosis transmembrane conductance regulator | polymer | 28 | 3256.7 | 2 | UniProt (P13569) In PDB | Homo sapiens | CFTR,ATP-binding cassette sub-family C member 7,Channel conductance-controlling ATPase,cAMP-dependent chloride channel |
| 3 | B, D | 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL | non-polymer | 208.3 | 2 | Chemie (ETE) | |||
| 4 | water | water | 18.0 | 735 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 232 (UniProt: P31946)
| PDB | External Database | Details |
|---|---|---|
| Met -2 | - | initiating methionine |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 114463.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 416.5 | |
| All* | Total formula weight | 114879.6 |
